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Gametes, embryos, and gestation: artificial wombs, in vitro gametogenesis, embryo selection, and inheritance made editable.
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A device that sustains fetal development outside a body by perfusing the umbilical circulation while the fetus remains immersed in fluid, tested so far only in animals.
A popular term for children whose traits are chosen before birth, covering a real but narrow practice of embryo selection and a largely hypothetical practice of embryo editing.
The development of a mammalian embryo or fetus outside a body, either for part of gestation or for all of it, and the ethical arguments the prospect generates.
Testing embryos created by IVF and choosing which to transfer, a routine clinical practice for single-gene disease whose extension to complex traits remains disputed.
The biological requirements of a crewed voyage lasting generations: population genetics, reproduction and development off Earth, and consent for people born in transit.
Producing a human genetically identical to an existing person by somatic cell nuclear transfer, demonstrated to the blastocyst stage and never taken to a pregnancy.
Modification of human embryos, eggs, or sperm so that the genetic change is inherited by the resulting child and by all of their descendants.
The routine clinical procedure in which eggs are fertilised outside the body and an embryo is transferred to a uterus, and the platform every other embryo technology is built on.
Making functional eggs or sperm from pluripotent stem cells in culture, achieved end to end in mice and still short of the meiotic stages in humans.
A set of IVF techniques that place a mother's nuclear DNA in a donor egg to prevent transmission of mitochondrial DNA disease, licensed in a few countries and used rarely.
The ranking of IVF embryos by polygenic risk scores computed from their inferred genotypes, sold commercially since 2019 and rejected as unvalidated by professional genetics bodies.
Julian Savulescu's principle that prospective parents have moral reason to select, among the children they could have, the one expected to live the best life.
The functional lifespan of the reproductive system, and efforts to extend it in the ovary, which loses function decades before most other organs.
Structures grown by aggregating stem cells that reproduce stages of early embryonic development without fertilisation, and the regulatory categories they fall outside.
A temporary transplant of a donated uterus that lets a woman without a working one carry a pregnancy, then is removed so that immunosuppression can stop.