Tag · 9 articles

reprogramming

Articles tagged reprogramming, drawn from 5 portals. Tags are assigned by hand and cut across the portal structure, so this set will not match any single subject area.

Longevity7 Genetics5 Organizations3 People2 Bodies1

Articles: 9
Portals spanned: 5
Words: 11k
Co-occurring tags: 22

9 of 9 shown

Altos LabsOrganizationsA biotechnology company launched in 2022 with about three billion dollars in committed funding to develop cellular rejuvenation programming as a medicine.2030sEmerging
David SinclairPeopleAustralian-American biologist at Harvard known for sirtuin and NAD+ research, the information theory of aging, and disputes over the strength of his public claims.presentContested
Epigenetic reprogrammingLongevityThe use of pluripotency factors to reset age-associated marks on DNA and chromatin, restoring youthful gene expression in cells without converting them into stem cells.TRL 32030sExperimental
Induced pluripotent stem cellsBodiesAdult cells reprogrammed back to an embryonic-like state, capable of becoming any cell type in the body and of being derived from a specific patient.TRL 7late 2020sEmerging
NewLimitOrganizationsA biotechnology company founded in 2021 to screen transcription-factor combinations that restore youthful function to aged cells without changing their identity.2030sEmerging
Partial reprogrammingLongevityTransient expression of pluripotency factors that resets age-associated epigenetic marks in a cell while stopping short of erasing its differentiated identity.TRL 32030sExperimental
Retro BiosciencesOrganizationsA longevity biotechnology company funded by Sam Altman with the stated goal of adding ten years of healthy life, working on autophagy, reprogramming and plasma-inspired therapies.2030sEmerging
Shinya YamanakaPeopleJapanese physician-scientist who showed that four transcription factors can reprogram adult cells to a pluripotent state, sharing the 2012 Nobel Prize for the discovery.presentEstablished
Yamanaka factorsGeneticsThe four transcription factors Oct4, Sox2, Klf4 and c-Myc, which together convert a differentiated cell into an induced pluripotent stem cell.TRL 7presentEstablished