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trl: 7trl: 7categories: ["cybernetics"]categories: ["cybernetics"]tags: ["bci", "microelectrodes", "neural recording", "braingate", "implants", "neurotechnology"]tags: ["bci", "microelectrodes", "neural recording", "braingate", "implants", "neurotechnology"]summary: "A silicon microelectrode array of 100 needles on a 10-by-10 grid, the standard sensor for chronic single-neuron recording in human brain–computer interface research."summary: "A silicon microelectrode array of 100 needles on a 10-by-10 grid, the standard sensor for chronic single-neuron recording in human brain-computer interface research."updated: "2026-07-27"updated: "2026-10-29"humanEvidence: "People with paralysis have used implanted arrays under investigational device exemptions to control cursors, robotic arms and speech decoders; some implants recorded usable signals beyond a thousand days."humanEvidence: "People with paralysis have used implanted arrays under investigational device exemptions to control cursors, robotic arms and speech decoders; some implants recorded usable signals beyond a thousand days."access: "Not a therapy: the US clearance covers recording for up to thirty days, and every long-term implant is placed in a research study under an investigational device exemption."access: "Not a therapy: the US clearance covers recording for up to thirty days, and every long-term implant is placed in a research study under an investigational device exemption."reversibility: "difficult"reversibility: "difficult"lines 30–51 → 30–4915 unchanged lines not shown
}}`````` **Utah array** is a silicon microelectrode array consisting of a grid of sharpened needles etched**Utah array** is a silicon microelectrode array: a grid of sharpened needles etched from a singlefrom a single block of silicon, inserted into the cortex so that each tip records the extracellularblock of silicon and inserted into the cortex, so that each tip records the extracellular voltagevoltage near a small number of neurons. Introduced at the University of Utah around 1990, it becamenear a small number of neurons. Introduced at the University of Utah around 1990, it became andand remains the standard sensor for chronic single-neuron recording in humans, and nearly everyremains the standard sensor for chronic single-neuron recording in humans. Nearly every major humanmajor human [[brain-computer-interface]] result involving individual action potentials has used[[brain-computer-interface]] result involving individual action potentials has used one.one. Its persistence is notable given how little it has changed. A device designed before the field hadIt has changed little since. A device designed before the field had a single human participant stilla single human participant still sets the performance benchmark that newer, higher-channel-countsets the performance benchmark against which newer designs with higher channel counts are measured.designs are measured against. ```keyfacts```keyfacts[[ { "value": "1991", "label": "First manufacturing description", "note": "Campbell et al., IEEE Transactions on Biomedical Engineering" }, { "value": "1991", "label": "First manufacturing description", "note": "Campbell et al., IEEE Transactions on Biomedical Engineering" }, { "value": "96", "label": "Channels typically wired", "note": "of 100 electrode sites on the grid" }, { "value": "96", "label": "Channels typically wired", "note": "of 100 electrode sites on the grid" }, { "value": "~4 mm", "label": "Footprint edge length", "note": "shanks usually 1.0–1.5 mm long" } { "value": "~4 mm", "label": "Footprint edge length", "note": "shanks usually 1.0-1.5 mm long" }]]`````` lines 58–74 → 56–726 unchanged lines not shown
The array is machined from a monolithic block of doped silicon. Dicing saws cut a grid of columns,The array is machined from a monolithic block of doped silicon. Dicing saws cut a grid of columns,which are then acid-etched into tapered needles on a 400-micrometre pitch, giving a device roughlywhich are then acid-etched into tapered needles on a 400-micrometre pitch, giving a device roughlyfour millimetres on a side with 100 electrode sites. The shanks, typically one to one and a halffour millimetres on a side with 100 electrode sites. The shanks, typically one to one and a halfmillimetres long, reach the cortical layers where pyramidal-cell somata are dense. The wholemillimetres long, reach the cortical layers where pyramidal-cell somata are dense. Everything exceptstructure except the tips is insulated with parylene-C; the exposed tips are coated with platinum orthe tips is insulated with parylene-C, and the exposed tips are coated with platinum or iridiumiridium oxide to lower impedance.[^campbell1991]oxide to lower impedance.[^campbell1991] Insertion is the tricky part. Pressed slowly, the array dimples the cortical surface rather thanInsertion is the difficult step. Pressed in slowly, the array dimples the cortical surface insteadpenetrating it, damaging tissue and pial vessels. A pneumatic inserter fires the array in at severalof penetrating it, damaging tissue and pial vessels. A pneumatic inserter fires the array in atmetres per second, which produces cleaner penetration.[^maynard1997] Wires from each shank runseveral metres per second, which produces cleaner penetration.[^maynard1997] Wires from each shankthrough a bundle to a connector; in the standard research configuration this is a percutaneousrun through a bundle to a connector. In the standard research configuration this is a percutaneoustitanium pedestal fixed to the skull, through which amplifiers are plugged in during sessions.titanium pedestal fixed to the skull, into which amplifiers are plugged during sessions. What the array measures is the extracellular field near each tip. Filtered above roughly 250 Hz andThe array measures the extracellular field near each tip. Filtered above roughly 250 Hz andthresholded, this yields action potentials from one to a few nearby neurons per channel; filteredthresholded, this yields action potentials from one to a few nearby neurons per channel; filteredbelow about 300 Hz, it yields local field potentials reflecting activity over a larger volume. Bothbelow about 300 Hz, it yields local field potentials reflecting activity over a larger volume. Bothfeed the decoders described under [[neural-decoding]].feed the decoders described under [[neural-decoding]].lines 76–121 → 74–1191 unchanged line not shown
## Development history## Development history Richard Normann's group designed the array in the late 1980s with a cortical visual prosthesis inRichard Normann's group designed the array in the late 1980s with a cortical visual prosthesis inmind — a grid of stimulating electrodes in visual cortex intended to evoke a pattern of phosphenes,mind: a grid of stimulating electrodes in visual cortex intended to evoke a pattern of phosphenes.the same goal that continues to motivate work described under [[retinal-implant]]. TheThe same goal still motivates the work described under [[retinal-implant]]. The manufacturingmanufacturing process was published in 1991 and the recording characterization followed through theprocess was published in 1991, and the recording characterization followed through the 1990s.1990s. Commercialization passed through several hands: Bionic Technologies, then CyberkineticsCommercialization passed through several hands: Bionic Technologies, then CyberkineticsNeurotechnology Systems, then Blackrock Microsystems, now Blackrock Neurotech. Cyberkinetics ranNeurotechnology Systems, then Blackrock Microsystems, now Blackrock Neurotech. Cyberkinetics ran thethe BrainGate pilot trial, in which Matthew Nagle, paralysed by a knife wound to the spinal cord,BrainGate pilot trial, in which Matthew Nagle, paralysed by a knife wound to the spinal cord,received an array in his motor cortex in 2004 and used it to move a cursor, open email, and operatereceived an array in his motor cortex in 2004 and used it to move a cursor, open email, and operatea prosthetic hand.[^hochberg2006] The BrainGate2 consortium — Brown, Massachusetts General Hospital,a prosthetic hand.[^hochberg2006] The BrainGate2 consortium (Brown, Massachusetts General Hospital,Stanford, and later UC Davis — has run the successor studies since.Stanford, and later UC Davis) has run the successor studies since. In the United States the array holds a clearance for temporary recording of up to thirty days,In the United States the array holds a clearance for temporary recording of up to thirty days, whichwhich supports intraoperative and epilepsy-monitoring use. Every long-term human implant issupports intraoperative and epilepsy-monitoring use. Every long-term human implant is conductedconducted under an investigational device exemption, not as approved therapy.under an investigational device exemption, not as approved therapy. ## Role in human BCI research## Role in human BCI research Because the array resolves individual neurons, it supports the highest-dimensional control yetBecause the array resolves individual neurons, it supports the highest-dimensional control yetdemonstrated. Robotic-arm control with multiple degrees of freedom, high-rate cursor typing, anddemonstrated. Robotic-arm control with multiple degrees of freedom, high-rate cursor typing, andseveral of the leading [[speech-neuroprosthesis]] results rest on Utah arrays, usually two toseveral of the leading [[speech-neuroprosthesis]] results rest on Utah arrays, usually two to fourfour implanted across motor and premotor areas; the fastest reported speech rates have come fromimplanted across motor and premotor areas. The fastest reported speech rates have come from surfacesurface grids rather than penetrating arrays, and the two approaches sit close together. It is also the sensor behind most attempts atgrids rather than penetrating arrays, though the two approaches sit close together. The array iswriting information back in through intracortical microstimulation, the route by which touchalso the sensor behind most attempts to write information back in through intracorticalpercepts have been delivered to users of [[neuroprosthetics]].microstimulation, the route by which touch percepts have been delivered to users of[[neuroprosthetics]]. A variant with shanks of graded length, the Utah slanted electrode array, is designed forA variant with shanks of graded length, the Utah slanted electrode array, is designed for peripheralperipheral nerve rather than cortex, and has been used to give sensation to users ofnerve rather than cortex. It has been used to give sensation to users of[[myoelectric-prosthetics]] — an early instance of the closed-loop principle that[[myoelectric-prosthetics]], an early instance of the closed-loop principle that[[sensory-augmentation]] research generalizes to senses the body never had.[[sensory-augmentation]] research extends to senses the body never had. Depth electrodes of other designs, rather than the Utah array, carry most of the human hippocampalMost of the human hippocampal work behind the [[memory-prosthesis]] literature uses depth electrodeswork behind the [[memory-prosthesis]] literature, because the relevant structures lie centimetresof other designs rather than the Utah array, because the relevant structures lie centimetres belowbelow the cortical surface that the array is built to sample.the cortical surface the array is built to sample. > [!note] What "96 channels" does and does not mean> [!note] What "96 channels" does and does not mean> Each channel may record several neurons whose spikes must be sorted, or none at all. The number> Each channel may record several neurons whose spikes must be sorted, or none at all. The number of> of channels yielding usable single units is generally well below the number wired, falls over> channels yielding usable single units is generally well below the number wired, falls over time,> time, and varies by implant site and participant. Reported channel counts are a property of the> and varies by implant site and participant. A reported channel count describes the hardware, not> hardware, not of the signal obtained.> the signal obtained. ## Failure modes and longevity## Failure modes and longevity lines 124–172 → 122–1672 unchanged lines not shown
years.[^simeral2011]years.[^simeral2011] The causes are mixed. Insertion injury and chronic micromotion provoke a foreign-body response:The causes are mixed. Insertion injury and chronic micromotion provoke a foreign-body response:microglia activate, astrocytes form an encapsulating sheath, and neurons retreat from the tip.microglia activate, astrocytes form an encapsulating sheath, and neurons retreat from the tip. TheIndependently, the device itself deteriorates — parylene insulation cracks and delaminates, tipdevice also deteriorates independently. Parylene insulation cracks and delaminates, tipmetallization corrodes, wire bonds and connectors fail. A systematic analysis in non-human primatesmetallization corrodes, and wire bonds and connectors fail. A systematic analysis in non-humanfound that material and mechanical failures accounted for a large share of losses, which mattersprimates found that material and mechanical failures accounted for a large share of losses. Thatbecause it implies that improving biocompatibility alone will not fixfinding implies that better biocompatibility alone will not fix longevity.[^barrese2013]longevity.[^barrese2013] Percutaneous pedestals add infection risk and prevent the user from living with the systemPercutaneous pedestals add infection risk and keep the user from living with the system untethered.untethered. This is the specific limitation that motivates fully implanted wireless designs,This limitation is what motivates fully implanted wireless designs, including [[neuralink]]'s sealedincluding [[neuralink]]'s sealed package and the surface arrays discussed underpackage and the surface arrays discussed under [[ecog-interfaces]].[[ecog-interfaces]]. ## Alternatives## Alternatives Three lines of work aim to displace the array. Higher-density silicon probes, most prominentlyThree lines of work aim to displace the array. Higher-density silicon probes, most prominentlyNeuropixels, put hundreds to thousands of recording sites along a single thin shank and have beenNeuropixels, put hundreds to thousands of recording sites along a single thin shank and have beenused acutely in human cortex during neurosurgery.[^jun2017][^paulk2022] Flexible polymer threads,used acutely in human cortex during neurosurgery.[^jun2017][^paulk2022] Flexible polymer threads, asas used by Neuralink, trade rigidity for reduced chronic tissue reaction but require roboticused by Neuralink, trade rigidity for a reduced chronic tissue reaction but require roboticinsertion. Non-penetrating approaches — subdural films and the endovascular [[stentrode]] — give upinsertion. Non-penetrating approaches, namely subdural films and the endovascular [[stentrode]],single-neuron resolution entirely in exchange for stability and lower surgical risk.give up single-neuron resolution entirely in exchange for stability and lower surgical risk. A fourth approach avoids metal electrodes altogether: [[optogenetics]] can read and write neuralA fourth approach avoids metal electrodes altogether. [[optogenetics]] can read and write neuralactivity optically, but requires genetically modifying the target neurons, which places it far fromactivity optically, but it requires genetically modifying the target neurons, which places it farroutine human use.from routine human use. None has yet accumulated a comparable human track record. That is the array's main remainingNone of these has yet built up a comparable human track record, and that is the array's mainadvantage: two decades of implants across multiple sites, with known failure statistics, againstremaining advantage. It has two decades of implants across multiple sites, with known failurecompetitors whose chronic behaviour in humans is largely unmeasured.statistics, while its competitors' chronic behaviour in humans is largely unmeasured. ## Outlook## Outlook The realistic future for penetrating arrays is not that they win or lose outright but that theyPenetrating arrays are more likely to specialize than to win or lose outright. Applications thatspecialize. Applications demanding many independent control dimensions — dexterous limb control,demand many independent control dimensions, such as dexterous limb control, fluent speech, and anyfluent speech, and any bidirectional system delivering fine sensory feedback — need single-neuronbidirectional system delivering fine sensory feedback, need single-neuron resolution that surfaceresolution that surface and vascular electrodes cannot supply. Applications needing a reliableand vascular electrodes cannot supply. Applications that need a reliable switch do not.switch do not. Whether that specialization survives depends on an unresolved empirical question: whether aWhether that specialization survives depends on an unresolved empirical question: can a penetratingpenetrating device can be built that still records well after ten years in a human brain. Thedevice be built that still records well after ten years in a human brain? The best-establishedbest-established implanted neurotechnologies, among them the [[cochlear-implant]] andimplanted neurotechnologies, among them the [[cochlear-implant]] and [[deep-brain-stimulation]],[[deep-brain-stimulation]], stimulate rather than record and sit in tissue that toleratesstimulate rather than record, and they sit in tissue that tolerates them for decades. No recordingthem for decades. No recording array has demonstrated equivalent durability, and the failurearray has shown equivalent durability, and the failure analyses suggest the answer depends as muchanalyses suggest the answer depends as much on materials engineering as on neuroscience.on materials engineering as on neuroscience. ## See also## See also removed, struck through added, underlinedLine numbers count the serialised markdown of each revision, frontmatter included.
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