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Aubrey de Grey

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categories: ["people", "longevity"]

tags: ["aging", "sens", "biogerontology", "life extension", "rejuvenation", "advocacy"]

summary: "British biogerontologist who proposed the SENS damage-repair framework for rejuvenation and popularized the idea of longevity escape velocity."

summary: "British biogerontologist who proposed the SENS damage-repair framework for rejuvenation and popularized the idea of longevity escape velocity."

updated: "2026-07-27"

updated: "2026-08-23"

issues: ["The 2021 misconduct section carries no citation for the investigation or its outcome."]

---

```infobox

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## Departure from SENS Research Foundation

In August 2021, two women in the longevity field publicly described inappropriate conduct by de

In August 2021, Laura Deming, founder of the Longevity Fund, and Celine Halioua, chief executive

Grey. The SENS Research Foundation placed him on leave, commissioned an independent legal

of the biotech company Loyal, publicly described sexual harassment by de Grey when they were young

investigation, and terminated his employment. De Grey denied wrongdoing and disputed the process.

scientists entering the field. STAT reported that the SENS Research Foundation placed him on leave

The episode split the organization and its donor base, and prompted broader discussion of conduct

pending an independent investigation, and that de Grey denied the allegations.[^stat2021] Later

norms in a field that depends heavily on a small number of private funders.

that month the foundation removed him as chief science officer, saying he had attempted to

interfere with the investigation.[^stat2021b] In September 2021 the investigating law firm, Van

Dermyden Makus, released an executive summary finding that he had made offensive sexual comments

to the two women; the foundation's board called the behaviour described unacceptable and

apologised to those affected.[^stat2021c] De Grey continued to dispute the findings and the

process. The episode split the organization and its donor base, and prompted broader discussion of

conduct norms in a field that depends heavily on a small number of private funders.

## Legacy and current work

Since 2022 de Grey has led the Longevity Escape Velocity Foundation, whose main programme is the

Since late 2022 de Grey has led the Longevity Escape Velocity Foundation, announced at the

Robust Mouse Rejuvenation study: rather than testing single compounds, it combines interventions

Longevity Summit Dublin that year.[^levf] Its main programme is the Robust Mouse Rejuvenation

already reported individually to extend mouse lifespan — [[rapamycin]] among them — and starts them

series: rather than testing single compounds, the first study combined four interventions already

in middle age, asking whether the effects add. That design addresses a real gap, since the field has

reported individually to extend mouse lifespan — [[rapamycin]], a senolytic, telomerase gene

run very few combination studies, and its results, whatever they show, are more checkable than any

therapy and hematopoietic stem-cell transplantation — starting at eighteen months of age, asking

of his forecasts.

whether the effects add.[^lt2022] That design addresses a real gap, since the field has run very

few combination studies, and its results, whatever they show, are more checkable than any of his

forecasts.

His durable influence is that he moved the question. Arguments that aging research was intrinsically

disreputable were common when he began; the [[geroscience-hypothesis]] is now respectable enough to

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[^ea2007]: `book` de Grey, A. and Rae, M. *Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime*. St. Martin's Press, 2007. {A trade book by the subject setting out his own programme; it argues that the repairs are feasible rather than reporting results.}

[^ea2007]: `book` de Grey, A. and Rae, M. *Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime*. St. Martin's Press, 2007. {A trade book by the subject setting out his own programme; it argues that the repairs are feasible rather than reporting results.}

[^tr2006]: `news` Pontin, J. "Is Defeating Aging Only a Dream?" *Technology Review* SENS Challenge report, 2006.

[^warner2005]: `paper` Warner, H. et al. "Science fact and the SENS agenda: What can we reasonably expect from ageing research?" *EMBO Reports*, 2005. {A signed commentary by a group of biogerontologists rather than a research paper; it reports their judgment of the SENS proposals.}

[^warner2005]: `paper` Warner, H. et al. "Science fact and the SENS agenda: What can we reasonably expect from ageing research?" *EMBO Reports*, 2005. {A signed commentary by a group of biogerontologists rather than a research paper; it reports their judgment of the SENS proposals.}

[^stat2021]: `news` Molteni, M. "Anti-aging research pioneer Aubrey de Grey placed on leave over sexual harassment allegations." *STAT*, 11 August 2021. {Reports the public accounts by Deming and Halioua, the foundation's decision to place de Grey on leave, and his denial.}

[^stat2021b]: `news` "SENS Research Foundation removes Aubrey de Grey over concerns he was interfering in sexual harassment investigation." *STAT*, August 2021.

[^stat2021c]: `news` Molteni, M. "Scientist Aubrey de Grey made inappropriate sexual comments to two female entrepreneurs, independent investigation finds." *STAT*, 11 September 2021. {Reports the release of the investigation's 18-page executive summary by the law firm Van Dermyden Makus and the board's response.}

[^levf]: `statement` Longevity Escape Velocity Foundation, levf.org. {The foundation's own description of itself and of Robust Mouse Rejuvenation as its flagship study; it is the claim of the organization de Grey leads, not independent reporting.}

[^lt2022]: `news` "Robust Mouse Rejuvenation project details announced." *Longevity.Technology*, December 2022. {A trade-press report of the study design: rapamycin, a senolytic, mTERT telomerase gene therapy and hematopoietic stem-cell transplantation, begun in 18-month-old mice at Ichor Life Sciences.}

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